By exploring the two core topics about “How to teach?” and “How to learn?”, we practiced the teaching reform based on the course Veterinary Molecular Virology. By renewing teaching concepts and improving teaching methods, and making use of “joint teaching” for “Professional type” and “Academic type” master degree training, we promoted the “covered” and “balanced” teaching to ignite students’ interests, strengthen learning process, improved learning efficiency, and inspired creative thinking. Navigated by the scientific questions designed during the teaching procedure, the students’ learning ability, thinking habit, and creativity could be strengthened through guiding the students’ active inquiry, deeply analyzing, and expanding the extended consciousness and behavior. Through the assessment of students’ knowledge, competence, and quality, highlights the concept of “trinity” of talent cultivation centering on knowledge inquiry, ability construction, as well as personality cultivation, and realizing the all-round promotion of innovative thinking and comprehensive ability, commit to the training of professional veterinary elites.