Bacterial sRNA is a class of noncoding RNA with 40?500 nucleotides in length. sRNA plays important roles in regulating gene expressions in response to diverse stresses in the environment. In this paper, we reviewed the progress of the research on the interaction between bacterial sRNA and quorum sensing system, which may be of great significance in revealing the intricate metabolic processes of bacteria, as well as understanding the mechanism of bacterial response to changes in the environment.