Supported by several national construction projects and based on the original foundation, we constructed a modern microbiology teaching system comprehensively with the guideline of textbook research and compilation. We produced a high level, full-scale textbook series with our own characteristics. We developed a powerful teaching team with members of different ages and all members pay the same attention to teaching and academic research. We also established a modern teaching method and system, while a pattern of “research learning” was created. Our effort promoted the national microbiology teaching level.