Experimental medical immunology and pathogenic biology is a new course which contains all experiment courses of medical microbiology, medical immunology, and medical parasitology. The teaching content was divided into three grades: Grade Ⅰ (foundation experiment), Grade Ⅱ (comprehensive experiment), and Grade Ⅲ (designing experiment), in which the designing experiment is not assigned definite titles. The students are required to think their own titles and then design and complete the designing experiment, using experiment skill and theoretical knowledge of the three subjects. Teaching of the new course can enhance practical skills, abilities of innovative thinking, and comprehensive qualities of the students. The new course deserves promotion to medical specialties after improved.