This article explores the strategy which makes students play the main role in teaching and teachers play an encouraging role by interactive teaching method in bilingual teaching of microbiology. Chinese textbooks and original English textbooks have been chosen carefully in order to “be helpful in achieving personnel training goal” and ensure cultivation quality; English has been used flexibly ac-cording to the student conditions in the bilingual teaching based on the available bilingual teaching re-sources; classroom vitality has been promoted by combining microbiology theory and practice, English lectures and debates, etc; the evaluation mode has been reformed reasonably and so on to enhance the bilingual microbiology education results.