The rapid development of network information technology has permeated into traditional classroom teaching, and changed the teaching idea, mode and organization style of classroom teaching. According to teaching model of “creating situations – asking questions – task decomposing – researching cooperatively – forming conclusion – evaluating online” utilization under network environment, network technology is fully integrated with microbiology curriculum teaching practice to realize the curriculum integrated with informational technology effectively. Teachers may try to change the existing teaching methods, avoid boring teaching, display the whole new perspective and improve teaching quality and results.