According to the cultivation objectives of the plant-productive specialities, the teaching contents and methods, testing forms and experimental teaching of the course of General Microbiology have been reformed. The reformation includes integrating, retrenching and updating the teaching contents, strengthening the fundamental knowledge, improving the classroom teaching methods and communicating in and after class in order to arouse the student’s interest and greatly spurs student’s initiative. The testing forms were also reformed to comprehensively evaluate the student’s ability of mastering and managing the knowledge. Through the reinforcement of the basic technical and scientific research training in the experiments, good teaching results have been achieved.