Medical Microbiology is an important basic course of medical specialties, with the characteristics of wide coverage of students and strong practicability. Carrying out ideological and political education in the Medical Microbiology is not only a fundamental measure of improving the ability to cultivate talent, but could also improve the teaching effect. In order to implement ideological and political education, teachers should not only improve their own abilities of ideological and political education, but also pay attention to the construction of ideological and political teaching team. In this paper, we discussed several cases of ideological and political education in Medical Microbiology in detail, so as to guide the medical students with correct values. Furthermore, cultivate their strong senses of social responsibility, social morality, good professional ethics, enhance their national self-confidence and cultural self-confidence, and enhance their patriotism.