COVID-19 is threatening the public health in China and oversea in the spring of 2020. During fighting against COVID-19, course teaching of Virus Biology for bachelor students in the school of life sciences has been adjusted to the new situation in the following aspects, aiming to help students establish scientific and rational viewpoints on the pandemic situation: Besides applying online teaching mode instead of offline mode, teaching contents on virology, epidemiology and public health were strengthened further. Besides the special speech on COVID-19 in the beginning of the new semester, a 5-min talk on COVID-19 has been presented for whole semester. These measurements during teaching of Virus Biology helped students understand scientifically and rationally this pandemic caused by virus infection and spreading. These teaching adjustments were necessary to inspire more interest in virology amongst students, epidemiology and public health, and will be improved with the change of this epidemic situation in China and oversea.