| 真菌生物信息学研究概况 |
| The general situation about bioinformatics of fungi |
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| 中文关键词:真菌，测序技术，生物信息学 |
| 英文关键词:fungi, sequencing technology, bioinformatics |
| 基金项目:漆酶在新型隐球酵母中调控相关蛋白的研究（No. 31100061） |
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| 中文摘要: |
| 真菌是真核生物的一大类群，主要包含酵母、霉菌之类的微生物以及最为人所熟知的菇类，无论是在生态、生命周期以及形态都有很大的差别。然而，到目前为止，对于真菌界的了解还很少，预估大约有150万个物种，之中已知种约占5%。1986年，美国科学家Thomas Roderick提出了基因组学概念，1990年代几个物种基因组计划的启动，揭开了历史性的一页。随着生物实验技术和信息处理技术的迅速发展与提高，生物信息学的概念应运而生，利用数学、信息学、统计学和计算机科学的方法研解决生物学的问题。介绍真菌的测序技术，概述了真菌基因组学、转录组学、蛋白质组学等方面的进展，并对真菌生物信息学的未来研究内容进行展望。 |
| 英文摘要: |
| Fungi are a major group of eukaryotes, including yeasts, molds, mushrooms and many others. There show huge differences in ecosystem, life cycle and morphology. There are about 1,500,000 species in the world, however, only 5% of them are currently known. The concept of genome was brought up by Thomas Roderick in 1986. The start up of several genomic projects in 1990s turned a new page. With the development and improvement of biological experiment technology, as well as information process technology, bioinformatics was born, which aims at resolution of biological problems by mathematics, informatics, statistics and computer science. The sequencing technologies and analytical approaches are described in this paper. Several fields, including genomics, transcriptoics and proteomics, are involved in fungal informatics and presented in this paper. The future research on the bioinformatics of fungi is prospected. |
| 姜楠,陈祖耕,朱旭东. 真菌生物信息学研究概况[J]. 菌物学报, 2013, 32(Z1): 115-126 |
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