灵芝多糖的生物合成和发酵调控 |
Biosynthesis and fermentation control of polysaccharides from Ganoderma lucidum |
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中文关键词:药用真菌,灵芝,生物合成,深层发酵,发酵策略 |
英文关键词:medicinal fungi, Ganoderma lucidum, biosynthesis, submerged fermentation, fermentation strategies |
基金项目:国家自然科学基金(No. 30700552);教育部高校博士点基金(No. 20094321120003);湖南省研究生科研创新基金资助项目(No. CX2010B315) |
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中文摘要: |
灵芝多糖是灵芝的关键药效成分之一。从灵芝多糖的结构和构效关系、灵芝多糖的单糖组成,灵芝主要多糖IPS-1-1的基本合成途径,以及灵芝多糖的深层发酵调控策略和方法等方面,综述了灵芝多糖生物合成和发酵调控方面的新进展。并对今后的主要研究方向进行了展望。 |
英文摘要: |
Ganoderma lucidum polysaccharides (GPS) are of the key pharmacologically active components of this medicinal fungus. Structure-activity relationship, constituents of monosaccharides of GPS, and basic biosynthetic pathways of the key GPS, IPS-1-1, as well as strategies and methods of fermentation control of GPS were reviewed. Further, future orientation in development of biosynthesis and fermentation control of GPS was discussed. |
刘高强,赵艳,王晓玲,朱朝阳. 灵芝多糖的生物合成和发酵调控[J]. 菌物学报, 2011, 30(2): 198-205 |
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